| Sabato 21/12/24 | AZ Alkmaar | 1 - 0 | Twente | |
|---|---|---|---|---|
| Domenica 15/12/24 | Twente | 2 - 0 | Groningen | |
| Giovedi 12/12/24 | EUL | Olympiakos Piraeus | 0 - 0 | Twente |
| Venerdi 06/12/24 | PSV Eindhoven | 6 - 1 | Twente | |
| Domenica 01/12/24 | Twente | 3 - 2 | Go Ahead Eagles | |
| Giovedi 28/11/24 | EUL | Twente | 0 - 1 | Union Saint-Gilloise |
| Sabato 23/11/24 | Fortuna Sittard | 1 - 2 | Twente | |
| Domenica 10/11/24 | Twente | 2 - 2 | Ajax | |
| Giovedi 07/11/24 | EUL | Nice | 2 - 2 | Twente |
| Sabato 02/11/24 | Willem II | 0 - 1 | Twente | |
| Domenica 27/10/24 | Twente | 5 - 0 | Heracles | |
| Giovedi 24/10/24 | EUL | Twente | 0 - 2 | Lazio |
| Sabato 19/10/24 | Waalwijk | 2 - 2 | Twente | |
| Domenica 06/10/24 | Feyenoord | 2 - 1 | Twente | |
| Giovedi 03/10/24 | EUL | Twente | 1 - 1 | Fenerbahce |
| Domenica 29/09/24 | Twente | 1 - 0 | NAC Breda | |
| Mercoledi 25/09/24 | EUL | Manchester United | 1 - 1 | Twente |
| Domenica 22/09/24 | Almere City FC | 0 - 5 | Twente | |
| Martedi 17/09/24 | Twente | 2 - 0 | Heerenveen | |
| Sabato 14/09/24 | Twente | 1 - 1 | Zwolle |